| 摘要： |
An efficient method for the oxidation of phenols to 1,4-benzoquinones catalyzed by cuprous(I) chloride was achieved in a solution of acetonitrile and water using molecular dioxygen as an oxidant. Particularly, the inert phenols, such as phenol and mono-alkyl substituted phenols, were effectively oxidized to 1,4-benzoquinones via the selective activation of C-H bond in para-position into C=O bond under mild conditions. The catalyst shows high activity for unsubstituted or alkyl substituted phenols, but no effect on substituted phenols with electron withdrawing groups. This study offers an aerobic method for the selective oxidation of aromatic phenols to 1,4-benzoquinones. |
